Orphaned at a very young age, Gui, a fourth-year engineering student, has had to work hard and earn for himself for as long as he can remember. Still, through the test of time, he still has a soft demeanor and a smile on his face. Solo, a freshman in the Faculty of Music, can get anything he wants with a flick of his wrist. Money, fame, good looks, the boy has everything, except his smile. When Solo's mother passed away, she took with her his smile. Nothing could fill this missing hole in him... that is — until one day when he sees a smiling boy working at a cafe. One night the two worlds collide in a small coffee shop. For a cup of hot milk and a warm smile, Solo finds himself back in the cafe every night. For a soft boy who reminds him of a husky, Gui finds himself waiting for a late-night visitor with a cup of hot milk, night after night. Night after night, the two boys continue to meet. At the same spot, at the same time, until they soon come to realize that they have become each other's breath. A necessity. Just like Oxygen.
Solo visits the coffee shop where Gui works late at night. When Solo order a coffee, Gui instead offers him a cup of warm milk to help him sleep. Solo begins to depend on Gui making this drink in order for him to sleep at night.
Gui makes plans to attend Solo's freshy competition but complications with the florist send the pair rushing to save the event. Kao works to ensure that Phuri will see him sing at the event. Dr. Petch panics after Khim convinces him he has all the signs of being attracted to men.
Gui helps Solo navigate the commitments of being the new campus representative. Kao helps nurse Phu back to health after he falls ill with a fever.
Solo notices a stranger is following him and Gui, taking their photos. Kao continues to find excuses to spend time with Phu. Kim gets the results back from her stay at the hospital.
Kay continues to pursue Gui despite Gui's insistence for it to stop. Tensions come to a head during the school service trip to the beach.
Following their trip, Solo invites Gui to move into his apartment. Phu comes to Kao's rescue after he is assaulted by a group of thugs.
Kao celebrates his birthday with friends and Phuri. Solo gives Jay a chance to explain why he disappeared years ago. Dr. Petch takes Khem on "dates" in order to secure photos to please Khim.
Gui makes a trip to meet with Mae Yai after learning of her failing health.
Solo, Gui, and Kao return to the farm where they are asked to step-in temporarily as teachers. Phuri and Kao take a hike to the waterfall together, but get lost, putting Phuri's daily call with his little brother at risk. Dr. Petch finds a way to secure an invite on Khim and Khem's trip.
Solo and Gui continue to help on the farm while trying to help Moon cope with the death of Mae Yai. Despite having a fever, Khem insists on continuing the trip to the waterfall with Khim and Petch.
Solo's father arrives to speak privately with Gui. Khem is devastates to learn that Dr. Petch has used him only to get closer to Khim. Phu and Kao prepare for a long distance separation.
While Linda makes life harder for Gui at his internship, Solo's father resorts to more extreme measure to control Solo. Kao says goodbye to Phu as he leaves for England.
Gui's important presentation day has arrived that will determine if he will pass his internship. Solo tries to reconcile with his father. Kao misses Phu dearly, but receives a surprise gift from his long distance boyfriend.
Complete episode guide for Oxygen The Series with detailed information about every season and episode including air dates, summaries, ratings, and streaming availability in France.
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