Top 10 Amazon Prime Video Shows You Must Watch (May 2025)
Amazon Prime Video continues to dominate the streaming landscape in 2025 with exceptional original content. From groundbreaking post-apocalyptic dramas to fantasy epics and award-winning comedies, we've curated the 10 best Amazon Prime shows you shouldn't miss this month. Whether you're looking for your next binge-watch or want to stay current with Prime Video's top series, this guide covers all the essential viewing.
Fallout ★ 4.8/5
Post-Apocalyptic Drama Sci-Fi ActionBased on the legendary video game franchise, Fallout delivers a gripping narrative set in a retro-futuristic post-nuclear America. The series follows survivors navigating the wasteland 200 years after the bombs fell, perfectly capturing the games' dark humor and moral dilemmas. With stunning production design that recreates the iconic 1950s aesthetic and new stories that expand the lore, Fallout has become one of 2025's most talked-about shows. The ensemble cast brings depth to both new characters and familiar factions like the Brotherhood of Steel.
Why Watch: A must-see for gamers and newcomers alike, offering one of the most faithful video game adaptations ever made.
The Boys: Gen V ★ 4.6/5
Superhero Drama SatireThis explosive spinoff from The Boys universe follows the next generation of supes at Godolkin University, Vought International's elite training ground. Season 2 delves deeper into the moral complexities of young superheroes grappling with their powers and corporate manipulation. Maintaining the franchise's signature dark humor and social commentary, Gen V introduces compelling new characters while weaving in connections to the main series. The show's unflinching take on celebrity culture and power dynamics makes it one of Prime Video's most relevant offerings.
Why Watch: Expands The Boys universe with fresh perspectives while delivering the same subversive superhero storytelling fans love.
The Wheel of Time ★ 4.5/5
Fantasy Adventure DramaAdapting Robert Jordan's monumental fantasy saga, The Wheel of Time reaches new heights in its third season. Covering events from 'The Shadow Rising,' the series follows Moiraine and her allies as they confront the Dark One's growing influence. With expanded world-building, breathtaking visuals, and deeper character development, Season 3 delivers the epic scale fans have been waiting for. The show's diverse cast and complex mythology continue to set it apart in the fantasy genre, offering a rich alternative to more mainstream options.
Why Watch: One of television's most ambitious fantasy adaptations, perfect for fans of intricate world-building and magical systems.
Reacher ★ 4.4/5
Action Thriller CrimeAlan Ritchson returns as Jack Reacher in another adrenaline-fueled season based on Lee Child's novels. The new installment finds the former military policeman uncovering a deadly conspiracy while demonstrating why he's one of fiction's most formidable protagonists. With brutal fight choreography, clever mysteries, and Ritchson's charismatic performance, Reacher continues to be one of Prime Video's most bingeable action series. The show's self-contained seasonal stories make it easy for new viewers to jump in while rewarding long-time fans.
Why Watch: Delivers old-school action hero thrills with modern production values and sharp writing.
The Legend of Vox Machina ★ 4.7/5
Animation Fantasy ComedyThis critically acclaimed animated series continues to push boundaries in its third season, adapting the beloved Critical Role Dungeons & Dragons campaign. Following the misfit adventurers of Vox Machina, the show blends epic fantasy storytelling with raunchy humor and heartfelt character moments. The stunning animation and voice work (performed by the actual Critical Role cast) create one of the most authentic D&D adaptations ever made. New viewers can easily enjoy the standalone adventures, while fans will appreciate deeper dives into character backstories.
Why Watch: A groundbreaking animated series that captures the spirit of tabletop RPGs like never before.
Fleabag ★ 4.9/5
Comedy Drama RomancePhoebe Waller-Bridge's masterpiece remains essential viewing years after its finale. Fleabag follows a sharp-witted but emotionally damaged woman navigating life, love, and family in London. The show's brilliant fourth-wall-breaking technique creates an unparalleled intimacy with viewers, while its blend of raunchy humor and profound emotional depth continues to influence contemporary comedy. Both seasons (especially the acclaimed second season featuring Andrew Scott as the Hot Priest) showcase television writing at its most innovative and affecting.
Why Watch: One of the 21st century's defining comedy series, with flawless writing and performances.
The Marvelous Mrs. Maisel ★ 4.8/5
Comedy Drama Period PieceAmy Sherman-Palladino's award-winning series concluded its five-season run with the same verve that made it a cultural phenomenon. Following Miriam "Midge" Maisel's journey from 1950s housewife to stand-up comedy pioneer, the show combines rapid-fire dialogue, lavish period detail, and Rachel Brosnahan's star-making performance. The complete series now stands as one of Prime Video's crown jewels, offering a binge-worthy exploration of gender roles, creative ambition, and the price of success. The supporting cast, including Alex Borstein and Tony Shalhoub, deliver equally memorable performances.
Why Watch: A visually stunning, brilliantly written period comedy with one of television's great female protagonists.
Étoile ★ 4.3/5
Drama Performing Arts RomanceFrom Amy Sherman-Palladino (The Marvelous Mrs. Maisel), Étoile offers a captivating look at the cutthroat world of professional ballet. The series follows dancers at a prestigious New York company as they navigate artistic rivalries, personal demons, and the physical toll of their art. With the same sharp dialogue and visual flair that defined Maisel, but applied to a completely different milieu, Étoile has emerged as one of 2025's standout dramas. The authentic dance sequences (performed by actual ballet stars) add to the show's immersive quality.
Why Watch: A rare quality drama about the performing arts, with Sherman-Palladino's trademark wit and style.
Mr. & Mrs. Smith ★ 4.2/5
Action Comedy SpyThis reimagining of the 2005 film stars Donald Glover and Maya Erskine as married spies juggling domestic life and high-stakes missions. The series format allows for deeper exploration of the central relationship while delivering spectacular action set pieces. Glover and Erskine's chemistry drives the show, which balances marital comedy with genuine suspense and emotional stakes. With its stylish direction and clever twists on spy genre conventions, Mr. & Mrs. Smith offers a fresh take that stands apart from both the original film and typical action fare.
Why Watch: A smart, character-driven spy series with outstanding lead performances and inventive action.
The Second Best Hospital in the Galaxy ★ 4.1/5
Animation Sci-Fi ComedyThis animated gem from creator Cirocco Dunlap offers a hilarious satire of medical dramas set in a futuristic alien hospital. Featuring voice work from Stephanie Hsu, Keke Palmer, and Maya Rudolph, the series tackles bizarre intergalactic medical cases with sharp humor and surprising heart. The imaginative alien designs and clever parody of hospital drama tropes make it one of Prime Video's most original offerings. While undeniably funny, the show also explores meaningful themes about healthcare, ethics, and what it means to be alive across different species.
Why Watch: A wildly creative animated series that blends sci-fi, comedy, and medical drama in fresh ways.
Looking for more streaming recommendations?
Check out our guides to the best Netflix shows and top HBO Max series for 2025.